Biochemistry
University of Utah Enzyme Discovery Enables Programmable Peptide Modifications for Next-Generation Diabetes and Obesity Treatments
University of Utah researchers have developed an enzyme technology that can stabilize and enhance therapeutic peptides for diabetes and obesity treatments, with the innovation now advancing toward clinical development through spinout company Sethera Therapeutics.
UCLA Researcher Peter Tontonoz to Receive 2025 American Heart Association Basic Research Prize for Lipid Metabolism Discoveries
Dr. Peter Tontonoz's groundbreaking research on cholesterol and lipid metabolism has transformed understanding of cardiovascular diseases and paved the way for new treatments beyond statins.
Sethera Therapeutics Announces Enzymatic Platform for Advanced Peptide Drug Development
Sethera Therapeutics has published research on an enzymatic platform that creates stable peptide structures, potentially enabling more effective and orally deliverable peptide therapeutics.
Study Reveals Environmental Contaminant 6-PPDQ Disrupts Citric Acid Cycle in C. elegans
Research highlights the potential environmental and human health risks posed by 6-PPDQ, a contaminant derived from tire antioxidants, through its disruption of the citric acid cycle in C. elegans.
Researchers Uncover Surprising Flexibility in Key Metabolic Enzyme Complex
A groundbreaking study reveals the dynamic structure of the pyruvate dehydrogenase complex, showing unprecedented flexibility that challenges previous understanding of cellular energy production. The research provides critical insights into metabolic processes with potential implications for disease treatment.